A Novel protocol for synthesis of Hantzsch 1, 4- dihydropyridines using PEG-400 as a reaction medium and under catalyst-free condition
نویسندگان
چکیده مقاله:
An efficient and expeditious catalyst-free procedure was developed for the one- pot synthesis of 1, 4-dihydropyridine derivatives via the three-component reaction of various aldehydes, ethyl acetoacetate, and ammonium acetate in PEG-400. The reaction was carried out at 110°С and the products were obtained in good to high yields.
منابع مشابه
Novel procedure for preparation of Hantzsch 1, 4- dihydropyridines using PEG-400 as a reaction medium and under catalyst-free condition
An efficient and expeditious catalyst-free procedure was developed for the one- pot synthesis of 1, 4-dihydropyridine derivatives via the three-component reaction of various aldehydes, ethyl acetoacetate, and ammonium acetate in PEG-400. The reaction was carried out at 110°С and the products were obtained in good to high yields.
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عنوان ژورنال
دوره 8 شماره 3
صفحات 5- 11
تاریخ انتشار 2018-10-15
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